Story byKyle Madson, Niners WireWed, January 7, 2026 at 5:18 AM UTC·1 min readThe impact of the San Francisco 49ers injury problems is hard to quantify after multiple stars missed all or most of the season. It's easy to overlook those injuries because of the team's 12-5 record and a return to the postseason. However, Over the Cap quantified the injury issues for all 32 teams by adding up how much salary cap space each club had on injured lists this season. Unsurprisingly, the 49ers topped the list with more than $95 million lost to players spending time on IR, PUP, NFI and the various suspended lists. AdvertisementAdvertisementAdvertisementHere's the explanation of their process:Reserve lists count for players on IR, PUP, NFI, SUS, etc…They do not count for players who were simply inactive.