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A massive gene hunt reveals how brain cells are made

Science News from research organizations A massive gene hunt reveals how brain cells are made Date: January 11, 2026 Source: The Hebrew University of Jerusalem Summary: A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this process possible. Among the discoveries is PEDS1, a gene now linked to a previously unknown neurodevelopmental disorder in children. When PEDS1 does not work properly, brain growth and nerve cell formation are impaired.

Neurons grown from stem cells in the lab form an interconnected network. In this study, researchers used CRISPR to switch off genes in stem cells and then followed how successfully the cells developed into neurons. Scale bar, 100 µm. . Galya Monderer-Rothkoff, The Hebrew University of Jerusalem

Neurons grown from stem cells in the lab form an interconnected network. In this study, researchers used CRISPR to switch off genes in stem cells and then followed how successfully the cells developed into neurons. Scale bar, 100 µm. . Galya Monderer-Rothkoff, The Hebrew University of Jerusalem

Credit: Dr

Key Highlights

  • The findings help explain how early genetic changes can shape brain development and disease.
  • Share: Facebook Pinterest LinkedIN Email FULL STORY Neurons grown from stem cells in the lab form an interconnected network.
  • In this study, researchers used CRISPR to switch off genes in stem cells and then followed how successfully the cells developed into neurons.
  • Scale bar, 100 µm.
  • Credit: Dr.
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Sources

  1. A massive gene hunt reveals how brain cells are made

This quick summary is automatically generated using AI based on reports from multiple news sources. The content has not been reviewed or verified by humans. For complete details, accuracy, and context, please refer to the original published articles.

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