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Louisville vs Duke Prediction, Picks & Best Bets for Tonight's College Basketball Game

Story byJason EnceMon, January 26, 2026 at 8:52 PM UTC·4 min readTwo of the ACC’s most explosive offenses collide tonight as the Louisville Cardinals head to Cameron Indoor Stadium to take on the Duke Blue Devils. Both teams are led by exciting freshmen in Mikel Brown Jr. and Cameron Boozer, but my Louisville vs. Duke predictions and college basketball picks center around Boozer's frontcourt mate, Patrick Ngongba II. AdvertisementAdvertisementAdvertisementLouisville vs Duke predictionLouisville vs Duke best bet: Patrick Ngongba II Over 9.5 points (-120)When the Duke Blue Devils and Louisville Cardinals met a few weeks ago, Duke starting center Patrick Ngongba II was involved in one of the more bizarre calls of the season. Midway through the first half, he and Louisville’s Kasean Pryor were each slapped with technical fouls as the two teams returned to the floor following a timeout.

Louisville vs Duke Prediction, Picks & Best Bets for Tonight's College Basketball Game

Credit: Yahoo

Key Highlights

  • Seconds later, the big man picked up his third foul and was done for some time. He ended up playing just 10 minutes in that game, scoring a season-low four points and attempting just four shots. AdvertisementAdvertisementAdvertisementGiven the extra motivation, I love getting his scoring total at 9.5 points.
  • This is a great matchup for him against a Louisville defense that has shown it can be pushed around inside by physical frontcourts. With the attention the Cardinals will have to pay towards Cameron Boozer, it’s unlikely they will afford any help defense.
  • And Ngongba has shown the ability to win those one-on-one matchups. Not only is he posting a 65.7% eFG% on the year, but he gets to the charity stripe often behind an eye-popping 75.7% free-throw rate.
  • That’s problematic for Louisville, which ranks 154th in sending players to the foul line. The Blue Devils attempt more than 44% of their shots from close range, and getting to the rim will be their focus against the Cardinals.
  • And in the four games since their prior meeting, he’s averaged 12.8 points. AdvertisementAdvertisementAdvertisementLook for Ngongba to have a double-digit scoring night at Cameron Indoor, where his scoring average is more than two points higher than what he manages away from home. Louisville vs Duke same-game parlayDuke’s emphasis on controlling the frontcourt leaves it vulnerable to outside shooting.
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Sources

  1. Louisville vs Duke Prediction, Picks & Best Bets for Tonight's College Basketball Game

This quick summary is automatically generated using AI based on reports from multiple news sources. The content has not been reviewed or verified by humans. For complete details, accuracy, and context, please refer to the original published articles.

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