Science News from research organizations Massive brain study reveals why memory loss can suddenly speed up with age Memory loss with age isn’t just about one brain region—it’s a whole-brain tipping point that can accelerate faster than expected. Date: January 14, 2026 Source: Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research Summary: A massive international brain study has revealed that memory decline with age isn’t driven by a single brain region or gene, but by widespread structural changes across the brain that build up over time. Analyzing thousands of MRI scans and memory tests from healthy adults, researchers found that memory loss accelerates as brain tissue shrinkage increases, especially later in life.