Story byPaul Bretl, Jaguars WireFri, December 19, 2025 at 2:52 PM UTC·2 min readWinners of five games in a row, the Jacksonville Jaguars travel to Denver in Week 16 for a matchup with the AFC-leading Broncos. So, who do the NFL experts have winning this matchup?Jacksonville currently is the three seed in the AFC at 10-4, and leads the AFC South division by a game over 9-5 Houston. AdvertisementAdvertisementAdvertisementWhen it comes to the top seed in the conference, the Jaguars are still in the mix, but in order to stay alive, a win over the 12-2 Broncos is a must. To see how these two teams stack up against one another and who has the advantage in certain areas, you can find that here. Denver head coach Sean Payton recently discussed the challenges that the Jaguars will present to this Broncos' team. Pro Football TalkMike Florio is picking the Broncos to win by four, while Chris Simms is taking the Jaguars to win by a field goal."How did this game end up in the 4:05 p. m. ET regional window?" Florio wrote. AdvertisementAdvertisementAdvertisementNFL. comFour of the five predictors from NFL. com are picking the Broncos to win in a one-score game. Here is why Tom Blair likes Denver:"The Texans were the last team to seriously pressure Lawrence, heating him up at a rate of 50% and sacking him five times, and that was also the last time the QB posted a passer rating under 80 (74.2).