Story by1 / 1NFL Moneyline Picks for Every Week 17 Game1 / 1NFL Moneyline Picks for Every Week 17 GameTrevor KnappFri, December 26, 2025 at 8:34 PM UTC·6 min readThe holiday season has arrived, and the upcoming schedule treats us to three Christmas games... albeit some slightly muddled matchups. Headlined by the Chicago Bears facing the San Francisco 49ers in a marquee Sunday Night showdown, I’ve got you covered with my favorite NFL picks for the entire Week 17 slate. AdvertisementAdvertisementAdvertisementWeek 17 NFL moneyline picksMatchupPick Cowboys vs Commanders<<-330>>Lions vsVikings<<-290>>Broncos vs Chiefs <<-1100>>Texans vsChargers<<+110>> Ravens vsPackers<<-136>>Cardinals vsBengals<<-375>>Seahawks vsPanthers<<-360>>Jaguars vsColts<<-300>>Patriots vsJets<<-1100>>Steelers vsBrowns<<-190>>Saints vsTitans<<-158>>Buccaneers vsDolphins<<-245>>Giants vsRaiders<<-120>>Eagles vsBills<<-136>>Bears vs49ers<<+146>>Rams vsFalcons<<-520>>Lines courtesy of FanDuel as of 12-23. Expert Week 17 NFL moneyline picksCowboys vs. Commanders: Cowboys (-330)First, Jayden Daniels was shut down for the remainder of the season.
