Key Highlights
- Louisville predictions and college basketball picks are backing the visitors in what should be a close game. AdvertisementAdvertisementAdvertisementDuke vs Louisville predictionDuke vs Louisville best bet: Duke +1 (-115)The Duke Blue Devils are national title contenders but have gone just 1-7 against the spread in their last eight games.
- That said, they've still lost just once this season and have four victories in Quad 1 games. Meanwhile, the Louisville Cardinals have been vulnerable since losing star freshman Mikel Brown Jr.
- to a back injury last month.
- They're coming off an upset loss to Stanford and have also lost lopsided contests to Tennessee and Arkansas since the start of December. Brown is Louisville's floor general and was averaging 16.6 points with a team-high 5.1 assists per game.
- This Cardinals offense hasn't flowed the same way without Brown, and their shooters are getting far fewer open looks from the perimeter. AdvertisementAdvertisementAdvertisementWhile Louisville will miss Brown, Duke is led by its own star freshman in Cameron Boozer (23.0 ppg, 9.8 rpg, 4.2 apg).