Story byKyle Madson, Niners WireSat, January 10, 2026 at 8:43 PM UTC·1 min readThe San Francisco 49ers open their 2025 NFL playoff slate Sunday with a matchup against the Philadelphia Eagles. What happens next if the 49ers are able to swing an upset?There are a handful of scenarios that could play out over the course of the NFC matchups on Saturday that would alter where the 49ers would be heading in the divisional round. AdvertisementAdvertisementAdvertisementHere's a quick reminder of the NFL playoff seeding:Seattle SeahawksChicago BearsPhiladelphia EaglesCarolina PanthersLos Angeles RamsSan Francisco 49ersGreen Bay PackersThe Panthers and Rams square off Saturday at 1:30pm Pacific Time. That'll be followed by the Packers visiting the Bears at 5:00pm Pacific Time. Only two things are certain.
